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Report of a Case

FRANK E. MEDFORD, MD

Arch Intern Med. 1965;116(4):589-593.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

IN 1939 Scott and Robb-Smith¹ studied a group of the reticuloses which had previously been described as "atypical Hodgkin's disease" or "lymphadenoma verum." Out of this study came a distinct clinicopathologic entity which they named "histiocytic medullary reticulosis." They reported four cases and referred to six other probable cases which were characterized by fever, wasting, generalized lymphadenopathy associated with hepatosplenomegaly, and in the final stage jaundice, purpura, and anemia with profound leukopenia. Histologically there was systematized hyperplasia of histiocytes actively engaged in erythrophagocytosis. In 1961 Zak and Rubin² reported a case of histiocytic medullary reticulosis and reviewed 25 other cases. They found no sex predominance, and the age range was from 26 to 78 years with a mean of 48 years. Survival ranged from 1 to 15 months with a median of 5 months. Three types of histiocytes were described; one had a pale, vesicular, elongated nucleus and . . . [Full Text PDF of this Article]

Author Affiliations
CHARLESTON, W VA

From Memorial Hospital, Charleston. Senior Resident in Medicine.

Footnotes
Received for publication Jan 18, 1965; accepted March 15.

Reprint requests to 3200 Noyes Ave, Charleston, W Va 25304. 03452.40352

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