This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

ULYSSES S. SEAL, PhD

Arch Intern Med. 1965;116(5):658-664.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

OUR conceptualization and operating knowledge of buffers and buffer mechanisms must, of necessity, have as their basis notions concerning the nature of acids and bases. The concurrent influence of two major theories of acids and bases, those of Arrhenius and Brønsted-Lowry, has resulted in much confusion concerning terminology and definitions in the areas of buffers and electrolytes.

The current vigorous exposition and application of the Brønsted-Lowry theory of acids and bases in clinical chemistry and in medicine has done much to clarify this confusion. However, it might be well to recognize that yet another, more general, acid-base theory, that of G. N. Lewis, is gaining in usefulness.

I will attempt to provide a mechanical-physical basis for the notions of acids and bases and their dissociation and then follow with a description of the properties of the Brønsted-Lowry theory which make it particularly well suited to biochemical systems. The theory of . . . [Full Text PDF of this Article]

Author Affiliations
MINNEAPOLIS

Biochemist, Minneapolis Veterans Hospital and Research Fellow, University of Minnesota.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?