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Case Study of a Husband and Wife

WILLIAM SCHAFFNER, MD; ALEXANDER C. McLEOD, MD; M. GLENN KOENIG, MD

Arch Intern Med. 1965;116(6):857-865.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

A MARRIED couple was admitted to Vanderbilt University Hospital in September 1964 with Rocky Mountain spotted fever. Two aspects of their disease appeared unusual: both patients became ill simultaneously and both manifested thrombocytopenia. Although attention has recently been called to the occurrence of thrombocytopenia with Rocky Mountain spotted fever, this association has been considered uncommon.^1-3 It is the purpose of this paper to report two further instances of this phenomenon, to survey the literature in this regard, and to suggest that thrombocytopenia occurs much more frequently during the course of Rocky Mountain spotted fever than is currently recognized. Similarly, a review of the literature supports the suggestion that small familial outbreaks of Rocky Mountain spotted fever are a significant, though generally unrecognized, aspect of the epidemiology of this disease.

Report of Cases

Patient A, a 50-year-old Caucasian woman, and patient B, a 51-year-old Caucasian man, were admitted to Vanderbilt . . . [Full Text PDF of this Article]

Author Affiliations
NASHVILLE, TENN

From the George Hunter Laboratory and the Department of Medicine, Vanderbilt University School of Medicine, Nashville. Dr. Schaffner is a postdoctoral fellow of the National Institute of Allergy and Infectious Diseases (No. I-F2-A1-23,120-01). Dr. Koenig is a Research Career Development Awardee, National Institute of Allergy and Infectious Diseases.

Footnotes
Received for publication April 22, 1965; accepted April 28.

Reprint requests to George Hunter Laboratory, Vanderbilt University School of Medicine, Nashville, Tenn 37203 (Dr. Schaffner).

Supported by ITS Public Health Service grant AI-03082, from the National Institute of Allergy and Infectious Diseases.

Milton Grossman, MD, permitted us to report these two cases. Dan B. Jones, MD, Epidemic Intelligence Service Officer from the Communicable Disease Center assigned to the Tennessee Department of Public Health, Nashville, Tenn, contributed invaluable assistance. Dr. Robert D. Collins, As-

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