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ALLEN CHINITZ, MD; FRANCIS L. TURNER, MD

Arch Intern Med. 1965;116(6):871-874.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

IT HAS BECOME evident in recent years that the syndrome of "inappropriate" secretion of antidiuretic hormone (ADH) ² is a manifestation of various diseases of multiple and unrelated etiologies.¹ The syndrome has been reported in association with bronchogenic carcinoma,² cerebral disease of several kinds^3-5 (neoplasm, vascular accidents, head trauma, malformations, tuberculous meningitis),^6,7 acute intermittent porphyria,^8,19 and tuberculosis (miliary and advanced pulmonary).⁹

The single endocrinological disturbance implicated in association with this syndrome to date has been hypothyroidism. Goldberg and Reivich ¹⁰ recently reported a case of myxedema manifesting impaired water excretion and hyponatremia consistent with inappropriate secretion of ADH. Their patient's hypothyroidism was secondary to the administration of radioactive iodine. We believe that we have observed the syndrome of inappropriate secretion of the antidiuretic hormone in a patient with primary (idiopathic) hypothyroidism.

Report of a Case

The patient (No. 09-65-71), a 73-year-old Spanish-American woman, was admitted to the Bernalillo County-Indian Hospital . . . [Full Text PDF of this Article]

Author Affiliations
ALBUQUERQUE, NM

From the Department of Medicine, The University of New Mexico School of Medicine, and the Bernalillo County-Indian Hospital, Albuquerque.

Footnotes
Received for publication Jan 22, 1965; accepted April 14.

Reprint requests to 6550th USAF Hospital, Patrick Air Force Base, Fla 32925 (Dr. Chinitz).

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