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REGINALD P. BRITT, MB, ChB; DAVID P. ROSE, MD

Arch Intern Med. 1966;117(1):32-33.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE PRESENT REPORT describes a case of addisonian pernicious anemia which was first recognized in a patient who was already known to be suffering from chronic granulocytic leukemia. The main point of interest is the level of vitamin B₁₂ in the serum, which was normal as estimated by microbiological assay despite the presence of other hematological evidence of vitamin B₁₂ deficiency.

Report of a Case

Initial Diagnosis.

—In October 1963 a housewife, 60 years of age, complained of breathlessness on exertion, abdominal discomfort, and occasional vomiting from which she had suffered for two months. She was hospitalized four years previously with symptoms related to chronic rheumatic heart disease. Slight macrocytosis of the red blood cells had been noted in the peripheral blood film at this time although she was not anemic (hemoglobin level, 14.1 gm/100 ml). A histamine fast achlorhydria had been demonstrated, but no further investigations had . . . [Full Text PDF of this Article]

Author Affiliations
SHEFFIELD, ENGLAND

From the departments of hematology and chemical pathology, Royal Infirmary, Sheffield, England.

Footnotes
Received for publication April 23, 1965; accepted July 28.

Reprint requests to University Department of Chemical Pathology, Royal Infirmary, Sheffield 6, England (Dr. Rose).

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