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Hospital-Acquired Aerobacter Cloacae InfectionsResults of Two Concomitant Studies
HAROLD D. ROSE, MD;
MARIE L. KOCH, PhD
Arch Intern Med. 1966;117(1):92-98.
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SINCE THE introduction and widespread use of antibiotic therapy in hospital practice, certain bacterial species heretofore considered to be nonpathogenic for man are now being recognized as causative agents of severe, and sometimes fatal, infectious disease. At the present time, among the most important of these so-called "opportunist pathogens" are the enteric and similar gram-negative bacilli of the Escherichia, Klebsiella, Proteus, and Pseudomonas genera, which comprise a part of the normal flora of the human body. According to recent reports,1-5 these organisms are now the scourge of the hospitalized patient, particularly in regard to the type of patient representative of our hospital population: the elderly, debilitated patient who has undergone extensive surgical procedures, or who may receive irradiation, corticosteroids, antineoplastic drugs, or indiscriminate antibiotic therapy.
Although the dangerous pathogenic potentialities of the abovementioned gram-negative bacilli are receiving worldwide attention, those relating to the genus Aerobacter (which are closely related
. . . [Full Text PDF of this Article]
Author Affiliations
MILWAUKEE
From the Medical and Laboratory Services, Wood Veterans Administration Hospital, and the departments of medicine and microbiology and Immunology, Marquette University School of Medicine, Milwaukee.
Footnotes
Received for publication April 15, 1965; accepted Aug 19.
Reprint requests to the Veterans Administration Center, S 54th St & W National Ave, Milwaukee, Wis 53193 (Dr. Rose).
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