This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (18)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

A Reappraisal

KELLY M. WEST, MD

Arch Intern Med. 1966;117(2):187-191.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

IT IS QUITE possible that means will soon be developed for identifying a specific defect in persons with genetically determined diabetes. But for the present the diagnosis still requires evidence of disturbed glucose tolerance. It has now been more than half a century since Jacobsen ¹ (1913) reported on the use of a glucose-loading test as a means of measuring carbohydrate tolerance. Other pioneers in this field included Hopkins,² and Hamman and Hirschman.³ These early workers observed that in contrast to normal persons those with diabetes exhibited blood sugar levels, after an oral glucose load, which were usually over 200 mg/100 ml at some time during the first hour and which failed to return to fasting levels by the third hour. Hamman and Hirschman ³ concluded in 1917 that: "In normal persons after ingestion of 100 gm of glucose, the blood sugar rises promptly to a level not . . . [Full Text PDF of this Article]

Author Affiliations
OKLAHOMA CITY

From the University of Oklahoma Medical Center, Oklahoma City.

Footnotes
Received for publication Aug 7, 1965; accepted Oct 26.

Reprint requests to 800 NE 13th St, Oklahoma City, Okla 73104.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?