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JOHN FORSHAW, MD; LILIAN HARWOOD

Arch Intern Med. 1966;117(2):203-205.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

A PECULIAR red blood cell with one or more large spiny projections along its periphery was designated "burr" cell by Schwartz and Motto.¹ These cells were observed in the blood of 73% of patients with uremia, 68% of patients with carcinoma of the stomach, and 54% of patients with bleeding peptic ulcer. Brain et al ² described 18 patients with acute renal failure and five with disseminated carcinoma, who developed overt hemolytic anemia and a bizarre blood picture characterized by numerous contracted, distorted, and fragmented red cells. Although these morphological abnormalities are now a well recognized feature in acute renal failure they are still regarded as unusual in cases of carcinoma and are not described in standard textbooks of hematology.^3,4 In the present paper we describe 17 cases of carcinoma, in which there was striking poikilocytosis.

Material and Methods

Over a two-year period a review was made of . . . [Full Text PDF of this Article]

Author Affiliations
MRCP; FIMLT, LIVERPOOL, ENGLAND

From the Sefton General Hospital, Liverpool 15, England.

Footnotes
Received for publication Aug 18, 1965; accepted Oct 5.

Reprint requests to the Sefton General Hospital, Liverpool 15, England (Dr. Forshaw).

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