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A Case Report With An Additional Diagnostic Aid

PHILIP S. CIFARELLI, MD; MATTHEW J. BENNETT, MD; EDWARD C. ZAINO, MD

Arch Intern Med. 1966;117(3):429-431.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

SJOGREN ¹ first reported a syndrome of xerostomia, keratoconjunctivitis sicca, and rheumatoid arthritis in 1933. It has been the subject of some more recent publication over the last decade,^2-8 some suggesting a relationship to lupus erythematosus,^9,10 others connective tissue diseases as well as malignant lymphoma.^12,13 Bunim^2,3,11,12 has given a clinical classification of the syndrome. It was Gougerot¹⁴ who first noted the association of xerostomia and keratoconjunctivitis with lymphocytic infiltration of the lacrimal glands. Morgan and Castleman ¹⁰ found that the histopathologic features of Mikulicz's disease and Sjogren's syndrome were indistinguishable with the latter having not only involvement of the salivary and lacrimal glands, but also systemic manifestations, the most frequent being rheumatoid arthritis.

We became interested in the minor salivary glands in this disorder and found it to be infrequently described.^2,9,15-17 Bain ⁹ pointed out that these glands may show the characteristic "benign lymphoepithelial lesion." The purpose of this report . . . [Full Text PDF of this Article]

Author Affiliations
EAST MEADOW, NY

From the departments of medicine and pathology, Meadowbrook Hospital, East Meadow.

Footnotes
Received for publication July 15, 1965; accepted Oct 7.

Reprint requests to Meadowbrook Hospital, Box 175, East Meadow, NY 11554 (Dr. Zaino).

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