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Human Intestinal Disaccharidase ActivityI. Normal Individuals
JACK D. WELSH, MD;
G. VICTOR ROHRER, MD;
ANTHONY WALKER, BS
Arch Intern Med. 1966;117(4):488-494.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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DECREASED disaccharidase activity in the small intestine may be primary, or secondary to other small intestinal diseases.1,2 The diagnosis is established by appropriate oral carbohydrate tolerance tests and assays of the mucosal disaccharidases of the small intestine. The work reported here concerns: (1) the oral lactose tolerance test in normal humans given varying amounts of the test carbohydrate; (2) our normal range of small intestinal disaccharidase and alkaline phosphatase activities; and (3) additional data on the distribution of these enzymes in the duodenum and jejunum.
Material and Methods
Patients.
—Twenty-five individuals were selected for this study on the bases of a negative history of milk or disaccharide intolerance and/or normal disaccharide tolerance tests. The subjects were then classified into two groups. Group 1 consisted of 19 presumably healthy individuals ranging in age from 21 to 46 years; 14 men and 5 women. Seventeen were Caucasian and two were
. . . [Full Text PDF of this Article]
Author Affiliations
OKLAHOMA CITY
From the Department of Medicine, the University of Oklahoma Medical Center, Oklahoma City.
Footnotes
Received for publication Oct 13, 1965; accepted Dec 27.
Reprint requests to 800 NE 13th St, Oklahoma City, Okla 73104 (Dr. Welsh).
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