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VINCENT T. DeVITA II, MD; JOHN P. UTZ, MD; TEMPLE WILLIAMS, MD; PAUL P. CARBONE, MD

Arch Intern Med. 1966;117(4):527-535.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE. HE CLINICAL and laboratory features of Candida meningitis were first described in 1933 by Smith and Sano.¹ Since that date, only 25 patients have been reported. Of these, only four have been successfully treated with amphotericin B.

The present report represents the fifth successfully treated patient with Candida meningitis further signified by occurring in a patient who was treated for blastic crisis of chronic myelogenous leukemia. Blastic crisis itself occurs in approximately 80% of patients with chronic myelogenous leukemia as a terminal disease.²

Thus, the occurrence of Candida meningitis successfully treated with amphotericin B, in a patient who also had a remission induced from a blastic crisis, is considered an opportune occasion to review the world's literature and summarize the clinical and laboratory findings and to discuss therapeutic results.

Report of Case

This white housewife (CC 04-28-67) was born June 1, 1896, and in good health until . . . [Full Text PDF of this Article]

Author Affiliations
NEW HAVEN, CONN; BETHESDA, MD

From the National Cancer Institute and the National Institute of Allergy and Infectious Diseases, Bethesda, Md.

Footnotes
Received for publication Nov 5, 1965; accepted Dec 20.

Reprint requests to the National Institutes of Health, Bethesda, Md 20014 (Dr. Carbone).

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