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Pathology of the Cardiac Conduction System in Polyarteritis Nodosa
THOMAS N. JAMES, MD;
ROBERT E. BIRK, MD
Arch Intern Med. 1966;117(4):561-567.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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THE HEART is often involved in polyarteritis nodosa and congestive failure is the second most frequent cause of death in this disease.1 Aneurysms of the coronary arteries were among the features first recognized in earlier studies 2 but are seen less often now; this is perhaps due in part to the effectiveness of anti-inflammatory therapy with adrenal corticosteroids. In a recent review of cardiac pathology observed in polyarteritis nodosa,3 the major manifestations were coronary arteritis (62%), myocardial infarction of various sizes (62%), and acute pericarditis (33%). Arrhythmias were described in only 9% and all these were supraventricular in origin; atrioventricular (AV) conduction disturbances were not reported. However, in the same series of patients tachycardia was present in 66%, being the second most frequent clinical cardiac finding.
Since the nutrient arteries of the sinus node and AV node are of the size (about 1 mm diameter) often involved
. . . [Full Text PDF of this Article]
Author Affiliations
DETROIT
From the Department of Medicine, Henry Ford Hospital, Detroit.
Footnotes
Received for publication Sept 21, 1965; accepted Jan 3, 1966.
Reprint requests to the Henry Ford Hospital, Detroit, Mich 48202 (Dr. James).
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