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  Vol. 118 No. 3, September 1966 TABLE OF CONTENTS
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Hypogammaglobulinemia in Hodgkin's Disease Treated With Nitrogen Mustard

ROBERT H. POE, MD; CLARK E. GABLE, MD; THOMAS JARROLD, MD

Arch Intern Med. 1966;118(3):199-202.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

HODGKIN'S disease is associated only rarely with hypogammaglobulinemia.1-4 In 53 patients at the Cincinnati Veterans Administration Hospital with Hodgkin's disease, in whom serum protein electrophoresis was performed, only one had significant hypogammaglobulinemia. This report presents the single case with documentation of the quantitative serum protein abnormalities and the heretofore unreported return to normal following nitrogen mustard therapy.

Report of a Case

A 35-year-old Negro man was admitted to the Cincinnati Veterans Administration Hospital in May 1964 with a three-month history of lower abdominal cramping pain and right upper quadrant post prandial discomfort, together with anorexia and weight loss approximating 27 lb (12.2 kg). For the preceding six weeks there had been intermittent dark urine and temperature spikes to 104 F (40.0 C) which had not responded to aspirin and antibiotic therapy. There had been no known exposure to hepatoxins, recent injections or blood transfusions, and no known contact with . . . [Full Text PDF of this Article]


Author Affiliations

CINCINNATI

From the Department of Medicine, University of Cincinnati College of Medicine, and the Medical Service, Hematology Section, Cincinnati Veterans Administration Hospital.


Footnotes

Received for publication April 27, 1966; accepted June 16.

Reprint requests to the Cincinnati Veterans Administration Hospital, Cincinnati 45220 (Dr. Jarrold).



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