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Renal Papillary Necrosis With Special Reference to Chronic AlcoholismA Report of 20 Cases
HUGH A. EDMONDSON, MD;
TELFER B. REYNOLDS, MD;
H. GRAM JACOBSON, MD
Arch Intern Med. 1966;118(3):255-264.
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IN recent years, in a study of the clinical and pathological aspects of liver disease in patients with chronic alcoholism, it was observed that acute renal failure due to papillary necrosis occurred in a significant number. None of the patients had diabetes mellitus, urinary tract obstruction, or a history of excessive use of analgesics. In a search of the literature, only five examples of the concomitant occurrence of cirrhosis and papillary necrosis were noted. Knutsen et al1 mentioned that cirrhosis was present in one of 16 cases of papillary necrosis, all proven either at autopsy or in surgical specimens. Cirrhosis was mentioned as being present at autopsy in two of 14 cases of the sclerotic type of papillary necrosis reported by Schourup.2 In reports of the other two patients, an elevated blood-glucose level was mentioned, so that diabetes mellitus could not be ruled out. One was an elderly
. . . [Full Text PDF of this Article]
Author Affiliations
LOS ANGELES
From the departments of pathology and medicine, University of Southern California School of Medicine and Los Angeles County Hospital.
Footnotes
Received for publication March 18, 1966; accepted April 27.
Reprint requests to 2025 Zonal Ave, Los Angeles 90033 (Dr. Edmondson).
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