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  Vol. 118 No. 5, November 1966 TABLE OF CONTENTS
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Sjögren's Syndrome and Nodular Reticulum Cell Sarcoma

JOHN H. HORNBAKER, JR., MD; EUGENE A. FOSTER, MD; GAYLORD S. WILLIAMS, MD; JOHN S. DAVIS IV, MD

Arch Intern Med. 1966;118(5):449-452.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

SJÖGREN'S syndrome is characterized by the clinical triad of keratoconjunctivitis sicca, xerostomia (with or without enlargement of the salivary glands), and rheumatoid arthritis. In some cases connective tissue disorders such as lupus erythematosus,1 polyarteritis nodosa,2 or scleroderma 3 may replace rheumatoid arthritis. Additional characteristic features include round cell infiltration of the salivary, lacrimal, and other exocrine glands, and the presence of multiple abnormal circulating globulins.

The association of Sjögren's syndrome and malignant lymphoma has been recognized recently,4 though the paucity of reported cases would suggest that it is rather uncommon. This report records the association of Sjögren's syndrome and nodular reticulum cell sarcoma in a patient dying after a profound hemolytic crisis with a markedly depressed serum complement level.

Report of a Case

A 78-year-old white woman had experienced burning of the eyes with the sensation of a foreign body, dryness of the mouth, and remittent enlargement . . . [Full Text PDF of this Article]


Author Affiliations

CHARLOTTESVILLE, VA

From the departments of medicine (Dr. Hornbaker), pathology (Dr. Foster), surgery (Dr. Williams), and preventive medicine (Dr. Davis), University of Virginia School of Medicine, Charlottesville, Va.; Reprint requests to University of Virginia School of Medicine, Charlottesville, Va (Dr. Davis).


Footnotes

Received for publication Dec 21, 1965; accepted June 20, 1966.



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