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Carcinomatosis of the Lung With Pulmonary HypertensionPathoradiologic Spectrum
L. REED ALTEMUS, MD;
ROBERT E. LEE, MD
Arch Intern Med. 1967;119(1):32-38.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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PULMONARY hypertension is a rare complication of lung carcinomatosis. Bristowe described the first case in 1868.1 Until 1961, only 17 cases appeared in the literature.2 Primarily, the discussions pertained to the unique clinical and pathological aspects, with little, if any, attention focused upon the associated roentgenographic findings.
Since the onset of symptoms and clinical course differed from either acute or chronic cor pulmonale, the term "subacute" cor pulmonale was advocated by Brill and Robertson in 1937.3 This terminology was used specifically for malignant tumor embolization of the lung. However, subsequent reports emphasized that nonmalignant emboli originating from veins or uterine trophoblastic elements may initiate the identical clinical picture.4-6 Furthermore, pure lymphangitic carcinomatosis may provoke sufficient changes within the pulmonary vascular bed to induce pulmonary hypertension and, in turn, the same characteristic clinical picture.7-9
A review of the literature and three cases encountered at Presbyterian-University Hospital disclosed a radiologie spectrum which
. . . [Full Text PDF of this Article]
Author Affiliations
PITTSBURGH
From the departments of radiology (Dr. Altemus) and pathology (Dr. Lee), Presbyterian-University Hospital, University of Pittsburgh, Pittsburgh.
Footnotes
Received for publication June 20, 1966; accepted Sept 29.
Reprint requests to the Department of Radiology, Magee-Womens Hospital of the University of Pittsburgh, Forbes Ave and Halket St, Pittsburgh 15213 (Dr. Altemus).
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