This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (17)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Case of Large Right-to-Left Shunt Surgically Corrected

David E. Dines, MD; O. Theron Clagett, MD; Robert A. Bonebrake, MD

Arch Intern Med. 1967;119(2):195-197.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Hereditary LEREDITARY hemorrhagic telangiectasia manifests itself by the formation of localized arteriovenous capillary connections that are tiny arteriovenous fistulas. The first comprehensive description was given by Rendu¹ in 1896. Osler² in 1901 and Weber³ in 1907 added to knowledge of the entity, which brought about the designation "Rendu-Osler-Weber syndrome." In 1909, Hanes⁴ used the term "hereditary hemorrhagic telangiectasia," which is the preferred designation.

Hodgson and colleagues⁵ studied 231 members of a large family of which 91 descendants had the disease entity. Of the descendants studied, 40% had telangiectasia and 6% had pulmonary arteriovenous fistulas. In 50% of the cases of pulmonary arteriovenous fistula, telangiectasia elsewhere in the body is encountered.⁶ Approximately 5% to 6% of patients with Rendu-Osler-Weber syndrome have pulmonary arteriovenous fistula.⁷

Pulmonary arteriovenous fistulas may occur in persons with or without hereditary hemorrhagic telangiectasia, but the close relationship makes it imperative that patients with this disorder be investigated . . . [Full Text PDF of this Article]

Author Affiliations
Rochester, Minn

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?