• Online Features  This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (78)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Correlation of Laboratory Studies and Clinical Data

Jack D. Welsh, MD; Victor Rohrer, MD; Maj Kermit B. Knudsen, USAF (MC); F. F. Paustian, MD

Arch Intern Med. 1967;120(3):261-269.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Several studies concerning isolated lactase deficiency have appeared recently.^1-9 Agreement has not been reached, however, concerning the interpretation of human intestinal disaccharidase activity ¹⁰ and the lactose tolerance test.^11,12 Previous studies from our laboratory reported early experience with oral tolerance tests using different amounts of lactose¹³ and described seven individuals with isolated lactase deficiency.^14,15 Through a cooperative study involving three medical centers, we have now accumulated data on 47 individuals with this defect. The current report compares the findings in these persons with those in a group of subjects with normal lactase activity and presents our concept of the significance of an isolated lactase deficiency based on these results.

Material and Methods

The studies were done on 170 individuals. There were 109 males, 61 females, 145 whites, 22 Negroes, and three American Indians. The patients ranged in age from 3 to 80 years with only three . . . [Full Text PDF of this Article]

Author Affiliations

From the Department of Medicine, University of Oklahoma Medical Center, Oklahoma City (Drs. Welsh and Rohrer); the Department of Medicine, Wilford Hall USAF Hospital, Aerospace Medical Division (AFSC), Lackland Air Force Base, Tex (Dr. Knudsen); and the Department of Medicine, University of Nebraska College of Medicine, Omaha (Dr. Paustian).

Footnotes

Read in part before the Third World Congress of Gastroenterology, Tokyo, Sept 23, 1966.

Reprint requests to 800 NE 13th St, Oklahoma City 73104 (Dr. Welsh).

CiteULike    Connotea    Delicious    Digg    Facebook    Reddit    Technorati    Twitter     What's this?