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Wall-Defective Bacteria
Morton Hamburger, MD
Arch Intern Med. 1968;122(2):175-178.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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The past two decades have witnessed many instructive revelations of the anatomy and biochemistry of the bacterial cell.1,2 These discoveries have stimulated great interest in the possible role, in clinical or experimental infection, of bacteria which differ from conventional bacterial forms.3-5 Are such organisms laboratory freaks or do they play a role in disease?
The terminology of bacteria wholly or partly deficient in their cell walls has become increasingly confused and is still subject to nuances of interpretation. The term L-form was coined in 1935 by Emmy Klieneberger, MD,6 to designate what she called "protoplasmic forms" derived from a strain of Streptobacillus moniliformis with which she was working at the Lister Institute in London. Not knowing exactly what she was dealing with, but needing a name, she called these aberrant organisms "L-forms," after the Lister Institute. Subsequent studies by microbiologists have resulted in the usual spate of
. . . [Full Text PDF of this Article]
Author Affiliations
Cincinnati
From the Department of Internal Medicine, Cincinnati General Hospital, Cincinnati.
Footnotes
Received for publication April 17, 1968; accepted May 21.
Reprint requests to 3231 Burnet Ave, Cincinnati 45229.
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