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Report of a Patient and Review of the Literature

Maj Ernest L. Mazzaferri, MC; Gerald M. Penn, MD

Arch Intern Med. 1968;122(6):521-525.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Since Moricz Kaposi's original description ¹ of "idiopathic multiple pigment sarcoma of the skin," nearly 1,000 publications have appeared documenting an estimated 1,200 patient summaries.^2,3 Reviews of this subject ^4-8 have established the frequent association with other neoplasms, among which lymphoreticular are the most common, especially Hodgkin's disease, lymphosarcoma, and lymphatic leukemia. In contrast, the reported association with multiple myeloma has been rare.^7,8

The purposes of this paper are as follows: (1) to describe a patient with multiple myeloma who developed classic lesions of Kaposi's sarcoma during treatment with an alkylating agent; (2) to suggest the possibility of a greater association of multiple myeloma with Kaposi's sarcoma than heretofore noted; and (3) to suggest the possible occurrence of serum protein abnormalities which may be due to Kaposi's sarcoma per se.

Patient Summary

A 63-year-old white male truck driver was in excellent health until June 1965, when he developed . . . [Full Text PDF of this Article]

Author Affiliations
USAF; Columbus, Ohio

Footnotes
Received for publication May 15, 1968; accepted July 29.

From the departments of medicine (Dr. Mazzaferri) and pathology (Dr. Penn), Ohio State University Hospital, Columbus, Ohio. Dr. Mazzaferri is now a postdoctoral fellow of the Department of Endocrinology and Metabolism at Ohio State University Hospital, and Dr. Penn is a fellow of the American Cancer Society.

The views expressed herein are those of the author and do not necessarily reflect the views of the Air University, the US Air Force, or the Department of Defense.

Reprint requests to 410 W Tenth Ave, Columbus, Ohio 43210 (Dr. Mazzaferri).

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