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Harris R. Clearfield, MD; Jerome I. Brody, MD; Henry J. Tumen, MD

Arch Intern Med. 1969;123(6):689-691.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Anemia which occurs in patients with viral hepatitis has been ascribed to transient hypersplenism, ineffective erythropoiesis with bone marrow megaloblastosis, and immune mechanisms.¹ More recently, attention has been drawn to glucose-6-phosphate dehydrogenase (G-6-PD) deficiency as an additional potential cause for the anemia sometimes observed in viral hepatitis.^2-4 The purpose of this report, therefore, is to describe three patients with this form of liver disease who also had G-6-PD deficiency, to emphasize that the hematologic abnormalities which may occur in this clinical combination are variable, and to outline the factors which may modify the different degrees of observed hemolysis.

Patient Summaries

PATIENT 1.

—A 29-year-old, previously healthy, Iranian physician was admitted to the Graduate Hospital of the University of Pennsylvania on April 7, 1966, because of generalized myalgia of four days' duration. His major complaint was preceded, in sequence, by a temperature of 102 F (38.9 C), dark urine, . . . [Full Text PDF of this Article]

Author Affiliations
Philadelphia

From the Department of Medicine, Graduate Hospital of the University of; Pennsylvania School of Medicine, Philadelphia.

Footnotes
Received for publication Nov 25, 1968; accepted Feb 18, 1969.

Reprint requests to 1727 Spruce St, Philadelphia 19103 (Dr. Clearfield).

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