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Joseph D. Feldman, MD

Arch Intern Med. 1969;123(6):713-718.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Graft rejection is the central process that begins almost immediately after foreign tissue is introduced to the host and that terminates usually some 8 to 12 days later in the death of the graft. The phenomenon occurs only in the living host and in all vertebrate species studied, and it includes several immunologic and nonspecific reactions that develop and progress in an apparently orderly sequence. It is the purpose here to describe the component reactions of the rejection process and to comment briefly on some methods of modifying the phenomenon so that grafting may be more successful.

Graft is used in this communication to mean homograft or exchange of tissue between individuals of the same species. The following are several types of graft: (a) avascular grafts such as corneal grafts; (b) those connected to a host by vascular anastomosis of two or more major vessels, eg, renal transplants; (c) those . . . [Full Text PDF of this Article]

Author Affiliations
La Jolla, Calif

From the Department of Experimental Pathology, Scripps Clinic and Research Foundation, La Jolla, Calif.

Footnotes
Received for publication Feb 6, 1969; accepted March 10.

Reprint requests to 476 Prospect St, La Jolla, Calif 92037 (Dr. Feldman).

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