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Rocky Mountain Spotted FeverA Vascular Disease
W. Lee Hand, MD;
Maj James B. Miller, MC;
Lt Col James A. Reinarz, MC;
Jay P. Sanford, MD
Arch Intern Med. 1970;125(5):879-882.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Prior to the introduction of broadspectrum antibiotics, Rocky Mountain spotted fever was a devastating disease. Subsequently, the mortality has dropped from 20% 1-3 to approximately 5%,2,4 and the illness is frequently considered to be benign if appropriately treated. The fact that the generalized vasculitis of Rocky Mountain spotted fever can be life-threatening in spite of prompt therapy with chloramphenicol or one of the tetracyclines is not always recognized. The following cases illustrate the complications of this vascular damage and emphasize the importance of appropriate management and therapy based upon an understanding of the pathophysiologic derangements.
Patient Summaries
PATIENT 1.
—A 35-year-old white man was hospitalized in June 1967 with a four-day illness characterized by chills, photophobia, headache, lassitude, nausea, vomiting, and diarrhea. A history of tick bites during a recent vacation on an Oklahoma farm was elicited. On admission he had a temperature of 105 F (40.6 C) and
. . . [Full Text PDF of this Article]
Author Affiliations
Dallas; USAF; USAF, Lackland Air Force Base, Tex; Dallas
From Wilford Hall USAF Hospital, Lackland Air Force Base, Tex (Maj Miller and Lt Col Reinarz), and the Department of Internal Medicine, University of Texas (Southwestern) Medical School at Dallas (Drs. Hand and Sanford).
Footnotes
Received for publication Nov 14, 1969; accepted Dec 30.
Reprint requests to 5323 Harry Hines Blvd, Dallas 75235 (Dr. Hand).
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