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George E. Granville, MD

Arch Intern Med. 1970;125(6):1041-1044.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Gonadotropin therapy has produced sperm in the ejaculum of several azoospermic patients with hypogonadotropic eunuchoidism,^1-6 pituitary gonadotropic insufficiency,⁷ and hypopituitarism following pituitary surgery.^8-10 In these studies the dosages of gonadotropin (s) have varied and one can not compare the potency of the preparations in regard to follicle-stimulating and interstitial cell-stimulating activities. A treatment program to achieve fertility in the hypopituitary man has not been established.

Patient Summary

A 29-year-old white man with hypopituitarism was admitted to the Veterans Administration Hospital, Houston, on April 19, 1966, for treatment of infertility.

His history disclosed these significant features: normal sexual development at puberty; onset of severe headaches and progressive visual loss in 1957; subtotal removal of a chromophobe adenoma of the pituitary gland at age 21 years on April 1, 1958, followed by irradiation (4,000 roentgens) of the pituitary area; use of adrenocortical therapy during surgery, and maintenance of his . . . [Full Text PDF of this Article]

Author Affiliations
Houston

From the Department of Medicine, Baylor College of Medicine and Veterans Administration Hospital, Houston.

Footnotes
Received for publication Jan 15, 1969; accepted Jan 26, 1970.

Reprint requests to 2002 Holcombe Blvd, Houston 77031 (Dr. Granville).

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