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Norman B. Finter, MB, BChir

Arch Intern Med. 1970;126(1):147-157.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In the virus interference phenomenon, first described 35 years ago,^1,2 a virus growing in particular cells in the animal body or in tissue cultures hinders the growth of a second virus subsequently brought into contact with the same cells. It has not proved possible to make use of this phenomenon for the control of human virus infections, except in a few instances.³ Nevertheless there have been many studies on the mechanisms responsible for interference, and it was during such a study that Isaacs and Lindenmann ⁴ discovered the proteins which they called "the interferon." Interferons are made by cells infected with a virus or exposed to certain other stimuli, and they have the important property of making other cells resistant to virus infection.

Isaacs and his colleagues at the National Institute for Medical Research, London, soon discovered the main properties of interferons, and it became apparent that these . . . [Full Text PDF of this Article]

Author Affiliations
Cheshire, England

From Imperial Chemical Industries Limited, Pharmaceuticals Division, Alderley Park, Macclesfield, Cheshire, England.

Footnotes
Received for publication Oct 15, 1969; accepted April 2, 1970.

Reprint requests to Imperial Chemical Industries Limited, Pharmaceuticals Division, Alderley Park, Macclesfield, Cheshire, England (Dr. Finter).

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