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Jan Vilek, MD; René I. Jahiel, MD

Arch Intern Med. 1970;126(1):69-77.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The effect doth operate another way.

Shakespeare

Troilus and Cressida

Act V, scene 3

Interferons are usually defined as cell-derived proteins, sharing certain common physicochemical properties, and characterized principally by their ability to render competent cells resistant to viral infections.^1-3 It seems that this definition will have to be modified to comprise the recently described effects of interferon on tumor growth and on the multiplication of infectious agents other than viruses. The action of interferon and interferon inducers on the growth of tumors is discussed in the accompanying communication by Levy. In this article we attempt to evaluate the action of interferon on the growth of infectious agents more complicated than viruses, viz, chlamydiae, rickettsiae, bacteria, fungi, and protozoa.

Evidence that interferon affects the multiplication of at least some members of these groups of infectious agents did come as a surprise, since it had been believed for many . . . [Full Text PDF of this Article]

Author Affiliations
New York

From the departments of microbiology and preventive medicine, New York University School of Medicine, New York.

Footnotes
Received for publication Oct 23, 1969; accepted Feb 11, 1970.

Reprint requests to 550 First Ave, New York 10016 (Dr. Vilek).

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