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Staphylococcus epidermidis Endocarditis Complicating a Starr-Edwards ProsthesisA Therapeutic Dilemma
Chatrchai Watanakunakorn, MD;
Morton Hamburger, MD
Arch Intern Med. 1970;126(6):1014-1018.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Endocarditis involving a prosthetic valve is a "disease of medical progress."1 It is a distinct entity and is becoming an important clinical problem as more and more cardiac valvular replacements are performed. For example, Yeh et al2 found that of 126 patients who undervent valvular replacements with Starr-Edwards prostheses, 9.5% developed endocarditis. It presents a therapeutic dilemma to the clinician, since the duration of antibiotic therapy has not been firmly established and the indications for removal of the presumably infected prosthesis are not always clear. In the face of bacterial colonization of intracardiac foreign material, treatment is extremely difficult regardless of the antibiotic susceptibility of the infecting organism. Occasional cases of apparently successful treatment with antibiotic alone3 on the one hand, and cases of failure of antibiotic therapy necessitating surgical removal of the infected prostheses on the other, have been recorded.3-5 The overall mortality is said
. . . [Full Text PDF of this Article]
Author Affiliations
Cincinnati
From the Department of Medicine, Division of Infectious Disease, University of Cincinnati College of Medicine, and the University of Cin-; cinnati Medical Center.
Footnotes
Received for publication April 24, 1970; accepted May 4.
Dr. Hamburger died July 29, 1970.
Reprint requests to Department of Medicine, K-4, Cincinnati General Hospital, Cincinnati 45229 (Dr. Watanakunakorn).
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