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  Vol. 128 No. 4, October 1971 TABLE OF CONTENTS
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Postmeningitic Selective Hypopituitarism With Suprasellar Calcification

Barry M. Sherman, MD; Phillip Gorden, MD; Giovanni di Chiro, MD

Arch Intern Med. 1971;128(4):600-604.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The finding of suprasellar calcification in a young male with diabetes insipidus and selective anterior putuitary insufficiency suggests the presence of a craniopharyngioma. However, calcifications at the base of the brain are common in patients successfully treated for tuberculous meningitis1-5 and both pituitary insufficiency and precocious puberty have been described as sequelae to cured tuberculous meningitis.6-8

Haslam et al9 have recently reported a patient with suprasellar calcifications who developed diabetes insipidus, growth failure, and hypogonadism following the successful treatment of tuberculous meningitis. We have studied a patient with similar hormonal deficiencies and intracranial calcifications occurring several years after the successful treatment of tuberculous meningitis. A suprasellar mass and hydrocephalus were excluded as causes of the hormonal deficiencies. This case further documents localized involvement by the tuberculous process as the cause of the endocrine syndrome.

Patient Summary

A 17-year-old Potawatomi Indian boy was referred to the Clinical Center . . . [Full Text PDF of this Article]


Author Affiliations

Bethesda, Md

From the Diabetes Section, Clinical Endocrinology Branch, National Institute of Arthritis and Metabolic Diseases (Drs. Sherman and Gorden) and the Section on Neuroradiology, National Institute of Neurological Diseases and Stroke, National Institutes of Health (Dr. di Chiro), Bethesda, Md.


Footnotes

Received for publication Oct 6, 1970; accepted Dec 30.

Reprint requests to Diabetes Section; Department of Health, Education, and Welfare; National Institutes of Health; Bethesda, Md 20014 (Dr. Gorden).



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