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Renal Cortical Necrosis in a Male AdultDocumented Recovery
W. Kline Bolton, MD;
Tito Cavallo, MD;
Edmund J. Lewis, MD
Arch Intern Med. 1973;131(2):265-269.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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The present report concerns a man with renal cortical necrosis. There was no apparent precipitating causative agent in this case. The renal pathologic findings of intravascular necrosis, occurring concommitant with an acute hemolytic anemia, characterized by the presence of the fragmented red blood cells of microangiopathic hemolytic anemia in the peripheral blood are similar to changes seen in children in the hemolytic-uremic syndrome (HUS).1-8 An increasing number of adult patients with bilateral renal cortical necrosis associated with microangiopathic hemolytic anemia (so-called HUS of adults) are now being reported9-16; however, most reports concern patients with predisposing diseases, such as obstetric complications.
Patient Summary
The patient is a 55-year-old black man who was admitted to the Boston City Hospital Fifth Surgical Service (Harvard) Jan 21,1970, with a four-day history of nausea, vomiting, malaise, general weakness, and anuria. No urine was obtained on urethral catheterization. His admission blood urea nitrogen (BUN)
. . . [Full Text PDF of this Article]
Author Affiliations
Boston
From the Harvard Medical Service, Boston City Hospital (Dr. Bolton); the Harvard Medical School and Mallory Institute of Pathology, Boston City Hospital (Dr. Cavallo); and the Harvard Medical School and Renal Division, Thorndike Memorial Laboratory, Boston City Hospital (Dr. Lewis), Boston. Drs. Bolton and Lewis are now with the Pritzker School of Medicine, University of Chicago, Chicago.
Footnotes
Received for publication Aug 24, 1971; accepted Jan 17, 1972.
Reprint requests to Pritzker School of Medicine, University of Chicago, Chicago 60637 (Dr. Lewis).
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