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Report of a Case

Barrett L. Bryan, MD; Carlos D. Espana, PhD; Richard W. Emmons, MD, PhD; Nazhiyath Vijayan, MD; Paul D. Hoeprich, MD

Arch Intern Med. 1975;135(6):868-870.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Since the original description of herpesvirus B encephalomyelitis by Sabin and Wright,¹ survival has been reported in but four patients— three recovered^2-4 and one died after 40 months in coma.⁵ We wish to record a fourth recovery. Our patient is additionally remarkable because he has no apparent residual neurological defects, except for diminished visual acuity of the left eye.

Herpesvirus simiae (HVS), a "B" virus or herpes B, is a natural parasite of Asian monkeys of the genus Macaca.^6,7 It is closely related to Herpesvirus hominis (HVH), which infects man.^8,9

The diagnosis of HVS infections in humans is accomplished readily in fatal cases because the virus can be recovered from brain tissue and identified in neutralization tests with antiserum to a known strain of HVS. Diagnosis prior to death, or in nonfatal cases, is more complicated, but B virus infection should be suspected in patients . . . [Full Text PDF of this Article]

Author Affiliations
From the Section of Infectious and Immunologic Diseases, Department of Internal Medicine, School of Medicine, and the California Primate Research Center, University of California, Davis; the University of California (Davis)-Sacramento Medical Center; and the California State Department of Health, Viral and Rickettsial Disease Laboratory, Berkeley.

Footnotes
Received for publication July 22, 1974; accepted Oct 2.

Reprint requests to School of Medicine, University of California, Davis, CA 95616 (Dr. Hoeprich).

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