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Hideyo Matsuguchi, MD; Masazumi Tsuneyoshi, MD; Akira Takeshita, MD; Motoomi Nakamura, MD; Toshihiko Kato, MD; Kikuo Arakawa, MD

Arch Intern Med. 1975;135(8):1110-1113.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Since Rosenwasser¹ reported the tumor of glomus jugulare in 1945, a number of cases have been reported; however, only a few cases showed evidence of catecholamine secretion.^2-5 Glomus jugulare tumor has been considered to originate embryologically in the neural crest and has been classified as a nonchromaffin paraganglioma because of the lack of chromaffinity. Previously only pheochromocytoma, among various neurogenic tumors, had been considered to secrete catecholamine, but since Mason et al⁶ in 1957 reported a case of adrenaline-secreting neuroblastoma, a close relationship of neurogenic tumors to abnormal catecholamine secretion⁷ has been recognized.

We report a noradrenaline-secreting tumor of the glomus jugulare with catecholamine granules shown electron microscopically. Continuous recording of blood pressure showed a peculiar cyclic change of the pressure.

METHODS

Catecholamine was measured by a modification of the trihydroxyindole fluorimetric method of von Euler and Floding.⁸ Levels of urinary total metanephrine (TMN) . . . [Full Text PDF of this Article]

Author Affiliations
From the Research Institute of Angiocardiology and Cardiovascular Clinic (Drs. Matsuguchi, Takeshita, Nakamura, and Arakawa) and the Department of Pathology (Dr. Tsuneyoshi), Kyushu University School of Medicine, and the Department of Oto-Rhino-Laryngology, Fukuoka University School of Medicine (Dr. Kato), Fukuoka, Japan. Dr. Arakawa is now at the Department of Internal Medicine, Fukuoka University School of Medicine, Fukuoka, Japan.

Footnotes
Received for publication April 11, 1974; accepted Feb 19, 1975.

Reprint requests to Research Institute of Angiocardiology and Cardiovascular Clinic, Kyushu University School of Medicine, 1276 Katakasu, Fukuoka, 812 Japan (Dr. Matsuguchi).

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