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Eleanor E. Sahn, MD; Steven A. Sahn, MD

Arch Intern Med. 1976;136(1):87-89.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Classical Wegener granulomatosis is a disease of unknown cause, characterized by necrotizing granulomatous involvement of the upper and lower parts of the respiratory tract, focal necrotizing glomerulitis, and necrotizing vasculitis involving both arteries and veins. The disease may involve multiple organ systems. First described in 1931¹ and 1936² and considered a rare disease, it is now recognized with increasing frequency. In 1954, Godman and Churg³ could find only 29 cases in the world literature. By 1967, there were at least 200 published cases, and several large series have been reported recently.^4-6

In 1966, Carrington and Liebow⁷ described a limited form of Wegener granulomatosis that appeared to have a better prognosis. They described 16 patients with characteristic pulmonary lesions but without the focal glomerulitis. Drachman,⁸ in 1963, reported that the frequency of neurological involvement in Wegener granulomatosis approximated 50% (Table). However, in his series of . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Internal Medicine and the Division of Pulmonary Medicine, University of Colorado Medical Center, Denver, and St Joseph's Hospital, Denver.

Footnotes
Received for publication March 3, 1975; accepted April 2.

Reprint requests to University of Colorado Medical Center, Box C 272, 4200 E Ninth Ave, Denver, CO 80220 (Dr S. Sahn).

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