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Saroja Bharati, MD; J. Pedro Bicoff, MD; Jaime L. Fridman, MD; Maurice Lev, MD; Kenneth M. Rosen, MD

Arch Intern Med. 1976;136(2):224-228.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Mesothelioma of the atrioventricular (AV) node, although a benign tumor, is a known cause of sudden cardiac death.¹ This association is surprising, in that the tumor location should produce a site of block proximal to the His bundle, which is ordinarily consistent with a favorable clinical course.^2-6

The present report concerns a 16-year-old girl with acquired heart block, sudden death, and pathological studies demonstrating a mesothelioma of the AV node. The case is unique in that His-bundle recordings were obtained that verified a localized site of AV block consistent with the location of the tumor. This case is of particular interest, since previous correlative studies of His-bundle recording and serial section of the conduction system have been attempted generally in patients with multiple electrophysiologic and pathologic sites of conduction disease,^7-12 rather than with a localized site as in our patient.

PATIENT SUMMARY

The patient was a gravida . . . [Full Text PDF of this Article]

Author Affiliations
From the Congenital Heart Disease and Research Training Center, Hektoen Institute for Medical Research; the Departments of Pathology, Northwestern University Medical School; Pritzker School of Medicine, University of Chicago; the Chicago Medical School, University of Health Sciences; Stritch School of Medicine, Loyola University; the departments of pathology and medicine, Abraham Lincoln School of Medicine, University of Illinois; Department of Pediatrics, Rush Medical College, Chicago, and St Francis Hospital, Evanston, Ill.; Dr Lev is a Career Investigator and Educator, Chicago Heart Association.

Footnotes
Received for publication March 26, 1975; accepted May 16.

Reprint requests to Congenital Heart Disease Research and Training Center, Hektoen Institute for Medical Research, 637 S Wood St, Chicago, IL 60612 (Dr Lev).

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