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Early Diastolic Sound Associated With Mitral Valve Prolapse
Anthony J. Bonner, Jr, MD;
R. Joe Noble, MD;
Harvey Feigenbaum, MD;
Morton E. Tavel, MD
Arch Intern Med. 1976;136(3):347-349.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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The prolapsing or billowing mitral valve syndrome has received much attention in recent years because of both its ubiquity and the occasional occurrence of serious problems in relation to it.1-4
Several physical findings have been related to this condition. The most striking and frequent finding is a midsystolic click (or clicks), which is followed frequently by a late systolic murmur.5,6 Some patients have had a holosystolic murmur, sometimes rather intense, without any click at all.5-7 Other patients demonstrate completely normal results of cardiac examinations in the presence of typical echocardiographic and angiographic evidence of prolapse.8,9
We have recently observed a patient with this syndrome who demonstrated, in addition to the midsystolic click and late systolic murmur, a striking early diastolic sound. Echocardiographic and phonocardiographic studies were carried out, along with pharmacologic interventions, in an effort to determine the nature of this sound.
PATIENT SUMMARY
A 37-year-old
. . . [Full Text PDF of this Article]
Author Affiliations
From the Department of Medicine, Indiana University School of Medicine, and the Krannert Institute of Cardiology, Indianapolis. Dr Bonner was a Public Health Service Trainee in Cardiology.
Footnotes
Received for publication May 30, 1975; accepted June 23.
Reprint requests to 110 Fesler Hall, Indiana University School of Medicine, 1100 W Michigan St, Indianapolis, IN 46202 (Dr Bonner).
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