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Lidocaine and His Bundle ExtrasystolesHis Bundle Discharge Conducted Normally, Conducted With Functional Right or Left Bundle-Branch Block, or Blocked Entirely (Concealed)
Anthony J. Bonner, MD;
Douglas P. Zipes, MD
Arch Intern Med. 1976;136(6):700-704.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Concealed discharge from the bundle of His was first postulated by Langendorf and Mehlman in 19471 to explain an unusual case of first- and second-degree atrioventricular (AV) block associated with junctional extrasystoles. Twenty-three years later, Rosen et al2 demonstrated the presence of concealed His bundle extrasystoles, and several subsequent reports have confirmed the observation.3-8
We present here another case demonstrating periods of PR prolongation and second-degree AV block mimicking types I and II, which resulted from concealed His bundle extrasystoles. The His bundle extrasystoles in this patient neither were coupled by a fixed interval to the previous QRS nor were they parasystolic; the His bundle extrasystoles either conducted normally, conducted with functional right bundle-branch block or functional left bundle-branch block, or blocked entirely, depending on the preceding cycle length and the coupling interval. These events afforded us a unique opportunity to study the effects of lidocaine on
. . . [Full Text PDF of this Article]
Author Affiliations
From the Krannert Institute of Cardiology, Department of Medicine, Indiana University School of Medicine, and the Veterans Administration Hospital, Indianapolis. Dr Bonner is a Public Health Service trainee in cardiology.
Footnotes
Received for publication Sept 15, 1975; accepted Sept 19.
Reprint requests to Indiana University School of Medicine, 1100 W Michigan St, Indianapolis, IN 46202 (Dr Zipes).
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