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Current Trends in Management and Diagnosis

Helmut Haibach, MD; Louis V. Avioli, MD

Arch Intern Med. 1976;136(6):725-731.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Douglas Biggs, MD, Senior Assistant Resident in Medicine, Jewish Hospital of St Louis, Assistant in Medicine, Washington University School of Medicine: A 19-year-old woman was admitted to Jewish Hospital for thyroid surgery in August 1974. In April 1973, she was examined because of excessive weight loss and fatigue. The thyroid gland was enlarged diffusely five to six times; a Murphy-Patte T₄ level was greater than 20µg/100 ml, and a six-hour sodiumiodide I 131 thyroid uptake was greater than 60%. The scan showed a diffusely enlarged gland, without nodules. Therapy with propylthiouracil, 100 mg four times a day, was started at that time. The dose of propylthiouracil was gradually increased during the next year, but the clinical response was less than adequate. In June 1974, the dosage of propylthiouracil was increased to 400 mg four times a day. After two months on this dosage regimen, the patient remained hyperthyroid clinically, . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Medicine, the Jewish Hospital of St Louis, and Washington University School of Medicine, St Louis.

Footnotes
Received for publication May 29, 1975; accepted June 11.

Reprint requests to 216 S Kingshighway, St Louis, MO 63110 (Dr Avioli).

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