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Prognosis for Recovery of Function in Acute Renal FailureValue of the Renal Image Obtained Using Iodohippurate Sodium I 131
Theodore H. Harwood, Jr, MD;
Dwight R. Hiesterman, MD;
Ralph G. Robinson, MD;
Donald E. Cross, MD;
Frederick C. Whittier, Jr, MD;
Dennis A. Diederich, MD;
Jared J. Grantham, MD
Arch Intern Med. 1976;136(8):916-919.
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The majority of patients who develop acute renal failure secondary to toxic or hypoxemic injury to nephrons eventually regain renal function sufficient to maintain life.1-3 However, even in patients who eventually recover, there is often a prolonged period of oliguria and azotemia prior to the onset of diuresis. In the oliguric or anuric period, conventional renal function tests are of no value in predicting the prognosis for recovery of renal function. Analysis of urinary concentration of electrolytes, creatinine, and urea, when there is sufficient urine to analyze, may confirm the diagnosis of renal tubular dysfunction,4,5 but the prognosis for recovery cannot be determined on that basis. Consequently, physicians generally adopt a "wait and see" approach with their patients in regard to the prospect for recovery of renal function.
Iodohippurate sodium I 131 (Hippuran 1-131) is not widely used in the assessment of acute renal failure, probably because the
. . . [Full Text PDF of this Article]
Author Affiliations
From the Division of Nephrology, Department of Medicine (Drs Harwood, Hiesterman, Diederich, Cross, Whittier, and Grantham), and the Division of Nuclear Medicine, Department of Diagnostic Radiology (Dr Robinson), University of Kansas Medical Center, College of Health Sciences and Hospital, Kansas City, and the Kansas City Veterans Administration Hospital, Kansas City, Mo.
Footnotes
Received for publication July 18, 1974; accepted Oct 2.
Reprint requests to Kansas City Veterans Administration Hospital, 4801 Linwood Blvd, Kansas City, MO 64128 (Dr Whittier).
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