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William R. Jacobs, MD; James V. Talano, MD; Leo Stephanides, MS

Arch Intern Med. 1977;137(7):911-913.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

A 25-year-old man was seen because of palpitations. Physical examination disclosed a slender man with a crescendo late systolic apical murmur. The ECG was normal, except for occasional premature ventricular beats. His echocardiogram and a superimposed apex phonocardiogram are shown in the Figure below.

What is your diagnosis?

Diagnosis.—Mitral Valve Prolapse

Sharp midsystolic sounds that Gallavardin (1913) believed were due to pleuropericardial adhesions were recognized as originating in the mitral apparatus by Griffith in 1892¹ and again by Reid² in 1961. Five years later, Barlow and Bosman angiographically demonstrated mitral prolapse.³ Echocardiographic findings were described by Shah and Gramiak⁴ in 1970 and by Dillon et al⁵ and Kerber et al⁶ in 1971. Careful physical examination has disclosed typical findings of mitral prolapse in 6%⁷ to 17%⁸ of presumably healthy young women. There often are associated skeletal deformities, such as pectus . . . [Full Text PDF of this Article]

Author Affiliations
From the Cardiology Section, Hines (Ill) Veterans Administration Hospital, and Stritch School of Medicine, Loyola University, Maywood, Ill.

Footnotes
Accepted for publication March 13, 1977.

Reprint requests to Cardiology Section, Hines Veterans Administration Hospital, Hines, IL 60141 (Dr Talano).

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