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Reduction of Myocardial Infarct SizeApproach for the 1980s
Ronald P. Karlsberg, MD;
Wilbert S. Aronow, MD
Arch Intern Med. 1980;140(5):616-619.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Early in the last decade, efforts were initiated to delineate the factors that influence the fate of the ischemic myocardium.1 As we enter a new decade, it is appropriate to extrapolate to the clinical situation the results of the numerous experimental efforts directed toward salvaging ischemic myocardium. We will, in this review, extract for the practicing physician the relevant advances in recent years. It is not our intention to present a complete review and bibliography on ischemic myocardium; rather, we hope to provide an approach that considers that interventions during acute myocardial infarction are potentially beneficial or detrimental.
THE BORDER ZONE
Central to the concept of salvaging ischemic myocardium is the concept that there is a "jeopardized," "border," "blighted," or "twilight" zone of ischemic tissue in the patient with acute myocardial infarction. Experimental work has shown that a portion of the tissue may either recover or continue to complete
. . . [Full Text PDF of this Article]
Author Affiliations
From the Cardiovascular Section, Medical Service, Veterans Administration Medical Center, Long Beach, Calif, and the University of California School of Medicine, Irvine.
Footnotes
Accepted for publication Sept 24, 1979.
Reprint requests to Cardiovascular Physiology, Veterans Administration Medical Center, 5901 E Seventh St, Long Beach, CA 90822 (Dr Karlsberg).
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