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Hepatitis B Antigen-Associated Periarteritis Nodosa With Prostatic VasculitisDiagnosis by Needle Biopsy
Don E. Cheatum, MD;
David S. Sowell III, MD;
Richard B. Dulany, MD
Arch Intern Med. 1981;141(1):107-108.
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The association of hepatitis B antigenemia with periarteritis nodosa (PAN) has been well described in the past decade1,2 and is probably caused by circulating immune complexes involving hepatitis B surface antigen (HBsAg).3 We describe a patient with prostatic vasculitis, a rather unusual presentation for PAN and one that is amenable to diagnosis by needle biopsy.
REPORT OF A CASE
A 55-year-old white man went to his physician with a six-week history of arthralgias, fatigue, and morning stiffness. He also complained of nocturia. A 2+ enlarged, irregular prostate was noted.
Abnormal findings on laboratory studies included an SGOT level of 258 mU/mL (normal, 7 to 40 mU/mL) and an alkaline phosphatase level of 123 mU/mL (normal, 30 to 115 mU/mL). Radioimmunoassay for HBsAg was positive initially and remained positive three months later, at which time testing for hepatitis B antibody was negative. An initial diagnosis of anicteric hepatitis was
. . . [Full Text PDF of this Article]
Author Affiliations
From the Departments of Internal Medicine (Drs Cheatum and Sowell) and Urology (Dr Dulany), Dallas Medical and Surgical Clinic and Baylor University Medical Center Hospital.
Footnotes
Accepted for publication March 31, 1980.
Reprint requests to Department of Rheumatology, Dallas Medical and Surgical Clinic, 4105 Live Oak, Dallas, TX 75221 (Dr Cheatum).
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