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John Laszlo, MD; Pat Cotanch, RN, PhD; Alan Stoudemire, MD
Durham, NC

Arch Intern Med. 1984;144(12):2433.

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In Reply.

—We agree that the capacity to induce amnesia is a desirable attribute of lorazepam and that this drug may have unique advantages in preventing or reducing anticipatory nausea and vomiting. Our own studies¹ remarked on the amnestic effect, though it was documented less often than by Greenspoon et al. Recent publications are also supportive of a salutary role for lorazepam alone or in combination with other agents.^2,3 Our current studies are in the direction of documenting whether lorazepam and metoclopramide are particularly effective when given together in patients receiving aggressive emetogenic therapy. There probably is an important role for both agents. . . . [Full Text PDF of this Article]

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