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A. NOSEDA, MD; M. Fuss, MD; N. DE NUTTE, MD; E. COGAN, MD; J. SCHMERBER, MD; J. CORVILAIN, MD
Brussels, Belgium

Arch Intern Med. 1989;149(5):1223.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—The watery diarrhea syndrome, best called vipoma syndrome, as it is mediated by a raised plasma vasoactive intestinal polypeptide (VIP) concentration, is known to be associated with pancreatic and neural crest, but not lung, tumors.¹ We describe a patient who presented with metastatic small-cell carcinoma of the lung (SCCL) and vipoma syndrome.

Report of a Case.—A 62-year-old woman was admitted for diarrhea, loss of weight, and back pain for several weeks. She had been a heavy smoker and drinker for many years. At the time of admission, she took no medication. Physical examination disclosed signs of dehydration and major liver enlargement. She had a watery diarrhea, exceeding 1.5 L daily. Results of laboratory tests showed the following results: urea nitrogen, 17.3 mmol/L; creatinine, 62 µmol/L; potassium, 2.5 mmol/L; arterial pH, 7.29; bicarbonate, 17 mmol/L; chloride, 112 mmol/L; calcium, 3.19 mmol/L; . . . [Full Text PDF of this Article]

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