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DERMOT KENNY, MD
Milwaukee, Wis

Arch Intern Med. 1990;150(9):1967-1971.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.— Fisher et al¹ in their article on n-3 fatty acids and cellular aspects of atherogenesis suggest that urgent trials of n-3 fatty acid supplementation are needed to assess their effects on atherosclerotic disease. While epidemiological studies^2,3 have documented a reduced incidence of ischemic heart disease in populations with a high intake of n-3 fatty acids, there is also an unexplained increased incidence of stroke.^2,3 Apart from a high incidence of unpleasant side effects in patients taking fish oil supplements, clinical⁴ and laboratory studies⁵ have shown evidence of raised blood pressure in groups taking omega-3 fatty acid supplementation. In addition, recent epidemiological evidence has shown an increased incidence and prevalence of hypertensive related diseases³ in the same type of population in whom there is a low incidence of ischemic heart disease. While the theoretical benefits of n-3 fatty acid supplementation are . . . [Full Text PDF of this Article]

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