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Norman M. Kaplan, MD

Arch Intern Med. 1991;151(7):1270-1272.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Two articles in this issue of the ARCHIVES^1,2 report different aspects of the major problem facing the 7 million diabetic patients in the United States—premature death from either coronary disease or nephropathy, which are now the leading causes of mortality in diabetics. Both articles present pessimistic data, one¹ suggesting lethal effects of the most widely used agent for the treatment of hypertension that is so common in diabetes, the other² portraying the frequent development of nephropathy over a short term. Despite the dour data, both articles also provide a window of opportunity that could significantly reduce the current excess of early mortality in diabetics.

THE THREAT OF DIURETIC THERAPY

Warram et al¹ present a retrospective analysis of the determinants of mortality in 759 diabetics, mostly insulin-dependent and middle-aged, followed up for a median of 4.5 years as part of a trial of laser therapy against blindness. . . . [Full Text PDF of this Article]

Author Affiliations
Department of Internal Medicine University of Texas Southwestern Medical Center at Dallas 5323 Harry Hines Blvd Dallas, TX 75235-8899

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