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Raphael B. Stricker, MD
San Francisco, Calif

Arch Intern Med. 1993;153(6):779.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In their excellent article on syphilitic meningitis in a human immunodeficiency virus-positive patient, DiNubile et al¹ focus on the patient's CD4 T-cell count of 1070 cells per cubic millimeter. According to the numbers in the article, the patient's CD8 T-cell count was approximately 4130 cells per cubic millimeter.

The authors spend the bulk of the report discussing the implications of a normal CD4 T-cell count in this setting. It seems ironic that the authors (like most of the medical establishment) are so fixated on CD4 T cells that they can ignore a CD8 T-cell count four times higher than normal in their patient. I would like to hear more about the implications of significantly increased CD8 T cells in neurosyphilis, since the role of these cells in human immunodeficiency virus disease may be quite important.^2,3 . . . [Full Text PDF of this Article]

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