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E. Ernst, MD
Exeter, Austria

T. Saradeth, MD; S. Seidl, MD; K. L. Resch, MD; O. Frischenschlager, MD
Vienna, Austria

Arch Intern Med. 1994;154(10):1166.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Several articles have suggested that low total cholesterol levels are linked to changes in behavior; men with low cholesterol levels are associated with higher rates of suicide within 6 years of measurement,¹ and lowering the cholesterol levels therapeutically by diets or drugs may lead to a rise in violent deaths.² One explanation for these somewhat disturbing findings is that a low plasma cholesterol level leads to modifications of brain cholesterol concentration that, in turn, alter central nervous function.³ Recent findings are highly contradictory, some speaking for^4-6 and some strongly against⁷ a relationship between blood lipid levels and psychologic variables. In this situation, a clinical study with a lipidlowering agent may lead further than epidemiologic evidence. We have undertaken a small pilot study quantifying psychologic variables in healthy volunteers during and after treatment with a fibrate.

Nine healthy individuals gave informed consent to participate (six men . . . [Full Text PDF of this Article]

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