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Javier Romo-Garcia, MD; Francisco Salido-Rengell, MD
Mexico City, Mexico

Arch Intern Med. 1994;154(11):1296-1298.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

As recently discussed by several authors, increased concentrations of lactate dehydrogenase (LDH) in patients with the acquired immunodeficiency syndrome (AIDS) and with altered chest roentgenograms strongly suggest a Pneumocystis carinii pneumonia.^1-4 A similar analysis was considered for Mycobacterium tuberculosis, a very frequent pathogen in Mexican patients with AIDS.

Specimens from 40 patients with AIDS were studied in a search for both mycobacteria and P carinii in sputum and/or bronchial washings with serum LDH determinations. Overall, the average LDH level was 508.65 IU. Eight patients (20%) were mycobacteria-positive, with an LDH medium of 525.20 IU, whereas 17 patients (42.5%) proved positive for P carinii with an LDH medium of 496.82 IU. Mycobacteria-negative patients had an LDH medium of 504.5 IU, while P carinii—negative patients had LDH media of 517.3 IU. Kruskal-Wallis analysis yielded a significant two-tailed test result (P=.05363), and a Mann-Whitney U analysis was rendered not significant. . . . [Full Text PDF of this Article]

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