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  Vol. 155 No. 1, 9 JANUARY 1995 TABLE OF CONTENTS
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Acute Renal Failure Attributable to Ciprofloxacin in a Patient With the Acquired Immunodeficiency Syndrome

M. Isabel Lucena, MD; Manuel Marquez, MD; José L. Velasco, MD; Raul J. Andrade, MD
Malaga, Spain

Arch Intern Med. 1995;155(1):114.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In a recent article, Lo et al1 found ciprofloxacin to induce nephrotoxicity in five patients with cancers. Ciprofloxacin was mainly indicated for the treatment of chemotherapy-induced neutropenic febrile episodes.

We report an acute renal failure that occurred in a patient with the acquired immunodeficiency syndrome (AIDS) within a few days of initiating ciprofloxacin therapy.

Report of a Case.

A 38-year-old man was admitted to the hospital because of cavitary pneumonia. He had been diagnosed as having had transfusion-associated AIDS and hepatitis C virus infection since 1991. There was a history of several opportunistic infections, including Pneumocystis carinii pneumonia, chronic cryptosporidiosis, and enterocolitis caused by Giardia lamblia.

Several days before admission to the hospital, he noticed severe weakness, fever, malaise, and a productive cough. The chest roentgenogram revealed a cavitary abscess with fluid in the left inferior lobe. A sputum culture yielded results positive for Pseudomonas aeruginosa

Intravenous antibiotic therapy . . . [Full Text PDF of this Article]



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