This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

John S. Yudkin, MD, FRCP
London, England

Arch Intern Med. 1995;155(12):1329-1330.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

G rover et al¹ used the Coronary Heart Disease Prevention Model to calculate the potential gains in life expectancy from two lifestyle changes: reduction in intake of saturated fat and smoking cessation. The Model is based on logistic regression data from the Framingham Heart Study,² the gains in life expectancy being calculated by applying preintervention and postintervention levels of total cholesterol and smoking vs nonsmoking status. Because the benefits of risk reduction may not be immediate, the authors recalculated gains in life expectancy with application of a 2- to 4-year lag period.

The problems inherent in this approach are clear from the meta-analyses of major intervention studies for hypercholesterolemia^3,4 and hypertension.⁵ From these overviews, two things become clear: (1) the reversibility of risk for coronary heart disease and stroke may be less than complete, particularly during the early stages of intervention; and (2) effects on noncardiovascular . . . [Full Text PDF of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?