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Another Case of the Need for Clinical Judgment

Timothy C. Fagan, MD

Arch Intern Med. 1995;155(20):2145.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

IN RECENT years, few medical topics have evoked the controversy, emotional response, media attention, and concern among patients equal to that surrounding the question of possibly increased mortality associated with calcium antagonists. In less than 6 months, there have been two metaanalyses involving patients with hypertension¹ and coronary heart disease², four accompanying editorials,^3-6 a statement from the National Heart, Lung, and Blood Institute,⁷ and innumerable articles in the lay press. Physicians have been bombarded by calls from concerned and frightened patients, and some patients have stopped their antihypertensive and antianginal therapy without consulting with their physicians.

See also pages 2150 and 2157

This question of possibly increased mortality with a class of drugs proven to produce improvement in symptoms and surrogate end points, eg, decreased blood pressure, is a quintessential example of the problems faced by practicing clinicians on a daily basis, ie, making clinical decisions . . . [Full Text PDF of this Article]

Author Affiliations
Deputy Editor Archives of Internal Medicine Suite 202A 2601 N Campbell Ave Tucson, AZ 85719

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